6YIL
Crystal structure of the CREBBP bromodomain in complex with a tetrahydroquinoxaline ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CREBBP | polymer | 119 | 14223.3 | 1 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (Human) | |
| 2 | A | (3~{R})-~{N}-[3-(3,4-dihydro-2~{H}-quinolin-1-yl)-2,2-bis(fluoranyl)propyl]-3-methyl-2-oxidanylidene-3,4-dihydro-1~{H}-quinoxaline-5-carboxamide | non-polymer | 414.4 | 1 | Chemie (OSQ) | |||
| 3 | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14223.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 414.4 | |
| All* | Total formula weight | 14637.8 |
