6YIJ
Crystal structure of the CREBBP bromodomain in complex with a benzo-diazepine ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | CREBBP | polymer | 119 | 14223.3 | 7 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (Human) | |
| 2 | A, B, C, D, E... | (4~{R})-6-[(~{E})-5-(7-methoxy-3,4-dihydro-2~{H}-quinolin-1-yl)pent-1-enyl]-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one | non-polymer | 405.5 | 7 | Chemie (OSN) | |||
| 3 | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 99563.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2838.7 | |
| All* | Total formula weight | 102402.2 |
