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6YIF

Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 1.8 A.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Baculoviral IAP repeat-containing protein 5polymer14416568.91UniProt (O15392)
Pfam (PF00653)
Homo sapiens (Human)Apoptosis inhibitor 4,Apoptosis inhibitor survivin
2B
(B)
Borealinpolymer678164.51UniProt (Q53HL2)
Pfam (PF10444)
Homo sapiens (Human)Cell division cycle-associated protein 8,Dasra-B,hDasra-B,Pluripotent embryonic stem cell-related gene 3 protein
3C
(C)
Inner centromere proteinpolymer516176.11UniProt (Q9NQS7)
Pfam (PF12178)
Homo sapiens (Human)
4D
(D)
Phosphorylated (Thr3) Histone H3polymer121388.51UniProt (by SIFTS) (P68431)Homo sapiens
5E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
6F, G, H
(A, B)
SULFATE IONnon-polymer96.13Chemie (SO4)
7I, J, K, L
(A, B, C, D)
waterwater18.0228Chemie (HOH)
Sequence modifications
A: 1 - 142 (UniProt: O15392)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight32298.0
Non-Polymers*Number of molecules4
Total formula weight353.6
All*Total formula weight32651.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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