6YI8
HUMAN FGFR4 KINASE DOMAIN (447-753) IN COMPLEX WITH ROBLITINIB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Fibroblast growth factor receptor 4 | polymer | 307 | 34342.7 | 2 | UniProt (P22455) Pfam (PF07714) In PDB | Homo sapiens (Human) | FGFR-4 |
| 2 | A, B | N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide | non-polymer | 506.6 | 2 | Chemie (FGF) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68685.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1493.4 | |
| All* | Total formula weight | 70178.7 |
