6YI8

HUMAN FGFR4 KINASE DOMAIN (447-753) IN COMPLEX WITH ROBLITINIB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Fibroblast growth factor receptor 4	polymer	307	34342.7	2	UniProt (P22455) Pfam (PF07714)	Homo sapiens (Human)	FGFR-4
2	C, G (A, B)	N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide	non-polymer		506.6	2	Chemie (FGF)
3	D, E, F, H, I (A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4	J, K (A, B)	water	water		18.0	238	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68685.3
Non-Polymers*	Number of molecules	7
	Total formula weight	1493.4
All*	Total formula weight	70178.7

*Water molecules are not included.