Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue FGF A 801 |
| Chain | Residue |
| A | LEU473 |
| A | CYS552 |
| A | ALA553 |
| A | ALA554 |
| A | GLY556 |
| A | LEU619 |
| A | SO4804 |
| A | HOH931 |
| A | HOH955 |
| A | GLY474 |
| A | ARG483 |
| A | THR499 |
| A | VAL500 |
| A | ALA501 |
| A | LYS503 |
| A | ILE534 |
| A | GLU551 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 802 |
| Chain | Residue |
| A | ARG563 |
| A | ARG566 |
| A | GLY687 |
| A | SER688 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 803 |
| Chain | Residue |
| A | ARG710 |
| A | PRO712 |
| A | HIS713 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 804 |
| Chain | Residue |
| A | ARG483 |
| A | FGF801 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 802 |
| Chain | Residue |
| B | LYS555 |
| B | ARG565 |
| B | ASN624 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 803 |
| Chain | Residue |
| B | ARG483 |
| B | FGF801 |
| B | HOH929 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide FGF B 801 and CYS B 552 |
| Chain | Residue |
| B | LEU473 |
| B | GLY474 |
| B | ARG483 |
| B | THR499 |
| B | VAL500 |
| B | ALA501 |
| B | LYS503 |
| B | ILE534 |
| B | VAL550 |
| B | GLU551 |
| B | ALA553 |
| B | ALA554 |
| B | GLY556 |
| B | LEU619 |
| B | SO4803 |
| B | HOH922 |
| B | HOH925 |
| B | HOH961 |
| B | HOH972 |
| B | HOH973 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGCFGQVVrAeafgmdparpdqast...VAVK |
| Chain | Residue | Details |
| A | LEU473-LYS503 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
| Chain | Residue | Details |
| A | CYS608-VAL620 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
