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6YG4

Crystal structure of MKK7 (MAP2K7) in complex with K00007

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dual specificity mitogen-activated protein kinase kinase 7polymer30734992.61UniProt (O14733)
Pfam (PF00069)
Homo sapiens (Human)MAPKK 7,JNK-activating kinase 2,MAPK/ERK kinase 7,MEK 7,Stress-activated protein kinase kinase 4,SAPKK4,c-Jun N-terminal kinase kinase 2,JNKK 2
2B, C, D, E, F...
(A)
1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
3H
(A)
(3Z)-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-1H-INDOL-2(3H)-ONEnon-polymer241.21Chemie (SU9)
4I
(A)
waterwater18.034Chemie (HOH)
Sequence modifications
A: 116 - 421 (UniProt: O14733)
PDBExternal DatabaseDetails
Ser 115-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34992.6
Non-Polymers*Number of molecules7
Total formula weight613.7
All*Total formula weight35606.3
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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