6YF1
FKBP12 in complex with the BMP potentiator compound 8 at 1.12A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peptidyl-prolyl cis-trans isomerase FKBP1A | polymer | 109 | 11990.7 | 1 | UniProt (P62942) Pfam (PF00254) In PDB | Homo sapiens (Human) | PPIase FKBP1A,12 kDa FK506-binding protein,FKBP-12,Calstabin-1,FK506-binding protein 1A,FKBP-1A,Immunophilin FKBP12,Rotamase |
2 | A | (1aR,3R,5S,6R,7S,9R,10R,17aS,20S,21R,22S,25R,25aR)-25-Ethyl-10,22-dihydroxy-20-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-5,7-dimethoxy-1a,3,9,21-tetramethyloctadecahydro-2H-6,10-epoxyoxireno[p]pyrido[2,1-c][1,4]oxazacyclotricosine-11,12,18,24(1aH,14H)-tetrone | non-polymer | 808.0 | 1 | Chemie (OP8) | |||
3 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 1 - 107 (UniProt: P62942)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 11990.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 808.0 | |
All* | Total formula weight | 12798.7 |