6YEN
Crystal structure of AmpC from E. coli with Taniborbactam (VNRX-5133)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 358 | 39587.9 | 1 | UniProt (P00811) Pfam (PF00144) | Escherichia coli K-12 | Cephalosporinase |
| 2 | B (A) | (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid | non-polymer | 389.3 | 1 | Chemie (KJK) | |||
| 3 | C (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 4 | D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | E, F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | H (A) | (10aR)-2-(((1r,4R)-4-((2-aminoethyl)amino)cyclohexyl)methyl)-6-carboxy-4-hydroxy-4,10a-dihydro-10H-benzo[5,6][1,2]oxaborinino[2,3-b][1,4,2]oxazaborol-4-uide | non-polymer | 388.2 | 1 | Chemie (K9K) | |||
| 7 | I, J (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 8 | K, L, M (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 9 | N (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 10 | O (A) | water | water | 18.0 | 345 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39587.9 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1525.2 | |
| All* | Total formula weight | 41113.2 |
