6YAX

Crystal structure of CD32b (Fc Gamma Receptor IIb) in complex with Human IgG1 Fab fragment (5C05)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (HHH, III)	5C05 F(ab) heavy chain	polymer	218	23210.9	2		Homo sapiens
2	B, D (MMM, LLL)	5C05 F(ab) light chain	polymer	218	22979.3	2		Homo sapiens
3	C, F (AAA, BBB)	Low affinity immunoglobulin gamma Fc region receptor II-c	polymer	181	20455.7	2	UniProt (P31995) Pfam (PF13895)	Homo sapiens (Human)	IgG Fc receptor II-c,CDw32,Fc-gamma RII-c,FcRII-c
4	G (A)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	H, K (HHH, III)	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
6	I (AAA)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
7	J (LLL)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	L, M, N, O, P... (HHH, MMM, AAA, LLL, III...)	water	water		18.0	277	Chemie (HOH)

Sequence modifications

AAA, BBB: 43 - 217 (UniProt: P31995)

PDB	External Database	Details
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	133292.0
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	4
	Total formula weight	701.8
All*	Total formula weight	134418.2

*Water molecules are not included.