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6YAL

Mammalian 48S late-stage initiation complex with beta-globin mRNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(1)
initiator methionylated tRNApolymer7524376.61Oryctolagus cuniculus (Rabbit)
2B
(l)
60s ribosomal protein ul41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)
Oryctolagus cuniculus (Rabbit)eL41
3C
(C)
40S ribosomal protein uS2polymer20923492.01UniProt (G1TLT8)
Pfam (PF00318)
Oryctolagus cuniculus (Rabbit)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
4D
(D)
40S ribosomal protein eS1polymer26429929.01UniProt (G1TN72)
Pfam (PF01015)
Oryctolagus cuniculus (Rabbit)
5E
(E)
40S ribosomal protein uS5polymer22624814.31Oryctolagus cuniculus (Rabbit)
6F
(F)
40S Ribosomal protein uS3polymer24326715.31UniProt (G1TNM3)
Pfam (PF00189)
Pfam (PF07650)
Oryctolagus cuniculus (Rabbit)
7G
(G)
40S ribosomal protein eS4polymer26329658.91UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Oryctolagus cuniculus (Rabbit)
8H
(H)
40S Ribosomal protein uS7polymer19121525.91UniProt (U3KMN4)
Pfam (PF00177)
Oryctolagus cuniculus (Rabbit)
9I
(I)
40S ribosomal protein eS6polymer23727471.51UniProt (G1TM55)
Pfam (PF01092)
UniProt (by SIFTS) (A0A5K1UJS7)
Oryctolagus cuniculus (Rabbit)
10J
(J)
40S ribosomal protein eS7polymer19221890.51UniProt (G1SVB0)Oryctolagus cuniculus (Rabbit)
11K
(K)
40S ribosomal protein eS8polymer20623902.91UniProt (G1TJW1)
Pfam (PF01201)
Oryctolagus cuniculus (Rabbit)
12L
(L)
40S ribosomal protein uS4polymer18221266.21UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
Oryctolagus cuniculus (Rabbit)
13M
(M)
40S ribosomal protein eS10polymer9811774.01UniProt (G1TPV3)
Pfam (PF03501)
Oryctolagus cuniculus (Rabbit)
14N
(N)
40S ribosomal protein uS17polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
Oryctolagus cuniculus (Rabbit)
15O
(O)
40S ribosomal protein eS12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)
Oryctolagus cuniculus (Rabbit)
16P
(P)
40S ribosomal protein uS15polymer15017128.21UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
Oryctolagus cuniculus (Rabbit)
17Q
(Q)
40S ribosomal protein uS11polymer15116302.81UniProt (G1T1F0)
Pfam (PF00411)
Oryctolagus cuniculus (Rabbit)
18R
(S)
40S ribosomal protein uS9polymer14115975.81UniProt (G1SGX4)
Pfam (PF00380)
Oryctolagus cuniculus (Rabbit)
19S
(T)
40S ribosomal protein eS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)
Oryctolagus cuniculus (Rabbit)
20T
(V)
40S ribosomal protein eS19polymer14115812.31UniProt (G1TN62)
Pfam (PF01090)
Oryctolagus cuniculus (Rabbit)
21U
(W)
40S ribosomal protein uS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)
Oryctolagus cuniculus (Rabbit)
22V
(X)
40S ribosomal protein eS21polymer828896.11UniProt (G1TM82)
Pfam (PF01249)
Oryctolagus cuniculus (Rabbit)
23W
(Y)
40S ribosomal protein uS8polymer13014865.61UniProt (G1TG89)
Pfam (PF00410)
Oryctolagus cuniculus (Rabbit)
24X
(Z)
40S ribosomal protein uS12polymer14315844.71UniProt (G1SZ47)
Pfam (PF00164)
Oryctolagus cuniculus (Rabbit)
25Y
(a)
40S ribosomal protein eS24polymer13315434.31UniProt (G1TS40)
Pfam (PF01282)
Oryctolagus cuniculus (Rabbit)
26Z
(b)
40S ribosomal protein eS26polymer11512961.51UniProt (G1TFE8)
Pfam (PF01283)
Oryctolagus cuniculus (Rabbit)
27AA
(c)
40S ribosomal protein eS27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)
Oryctolagus cuniculus (Rabbit)
28BA
(d)
40S ribosomal protein eS28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)
Oryctolagus cuniculus (Rabbit)
29CA
(e)
40S ribosomal protein uS14polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)
Oryctolagus cuniculus (Rabbit)
30DA
(f)
40S ribosomal protein eS31polymer718358.91UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
Oryctolagus cuniculus (Rabbit)
31EA
(g)
ribosomal protein RACK1polymer31334669.11UniProt (G1SJB4)
Pfam (PF00400)
Oryctolagus cuniculus (Rabbit)
32FA
(n)
40S ribosomal protein eS25polymer12413645.01UniProt (G1TDB3)
Pfam (PF03297)
Oryctolagus cuniculus (Rabbit)
33GA
(i)
40S ribosomal protein eS30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)
Oryctolagus cuniculus (Rabbit)
34HA
(2)
18S ribosomal RNApolymer1863601015.71Oryctolagus cuniculus (Rabbit)
35IA
(A)
Eukaryotic translation initiation factor 2 subunit alphapolymer28432792.91UniProt (G1T2G4)
Pfam (PF00575)
Pfam (PF07541)
Oryctolagus cuniculus (Rabbit)
36JA
(B)
Eukaryotic translation initiation factor 2 subunit gammapolymer42245862.41Pfam (PF00009)
Pfam (PF03144)
Pfam (PF09173)
UniProt (by SIFTS) (A0A6P3CWF8)
Oryctolagus cuniculus (Rabbit)
37KA
(j)
eukaryotic translation initiation factor 1Apolymer11112788.81Pfam (PF01176)
UniProt (by SIFTS) (G1SYS4)
Oryctolagus cuniculus (Rabbit)
38LA
(k)
ATP-binding cassette sub-family E member 1 (ABCE1)polymer59566986.81Pfam (PF04068)
Pfam (PF00037)
Pfam (PF00005)
UniProt (by SIFTS) (G1SG72)
Oryctolagus cuniculus (Rabbit)
39MA
(U)
40S ribosomal protein uS13polymer15217759.81UniProt (G1TPG3)
Pfam (PF00416)
Oryctolagus cuniculus (Rabbit)
40NA
(R)
40S ribosomal protein uS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)
Oryctolagus cuniculus (Rabbit)
41OA
(3)
beta-globin mRNApolymer4213475.11Homo sapiens
42PA, QA
(k)
IRON/SULFUR CLUSTERnon-polymer351.62Chemie (SF4)
43RA
(k)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
44SA, TA
(k)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.22Chemie (GNP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains41
Total formula weight1388399.0
Non-Polymers*Number of molecules5
Total formula weight1772.0
All*Total formula weight1390171.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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