6Y6S

Mouse Galactocerebrosidase complexed with galacto-noeurostegine GNS at pH 6.8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Galactocerebrosidase	polymer	654	74596.8	1	UniProt (P54818) Pfam (PF02057) Pfam (PF17387) Pfam (PF21708)	Mus musculus (House mouse)	GALCERase,Galactocerebroside beta-galactosidase,Galactosylceramidase,Galactosylceramide beta-galactosidase
2	B, C, D (B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
3	E (A)	(1~{R},2~{S},3~{S},4~{R},5~{R})-4-(hydroxymethyl)-8-azabicyclo[3.2.1]octane-1,2,3-triol	non-polymer		189.2	1	Chemie (ODW)
4	F (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	G (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
6	H (A)	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
7	I (A)	water	water		18.0	267	Chemie (HOH)

Sequence modifications

A: 25 - 668 (UniProt: P54818)

PDB	External Database	Details
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
Ile 21	-	expression tag
Glu 22	-	expression tag
Gly 23	-	expression tag
Arg 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	74596.8
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	4
	Total formula weight	509.2
All*	Total formula weight	76379.1

*Water molecules are not included.