6Y6F

Crystal structure of STK17B (DRAK2) in complex with PKIS43

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine/threonine-protein kinase 17B	polymer	327	37327.1	1	UniProt (O94768) Pfam (PF00069)	Homo sapiens (Human)	DAP kinase-related apoptosis-inducing protein kinase 2
2	B (A)	2-[6-(4-methylsulfanylphenyl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic acid	non-polymer		348.5	1	Chemie (OD2)
3	C, D, E, F (A)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
4	G (A)	water	water		18.0	284	Chemie (HOH)

Sequence modifications

A: 25 - 329 (UniProt: O94768)

PDB	External Database	Details
Met 3	-	initiating methionine
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Ser 10	-	expression tag
Ser 11	-	expression tag
Gly 12	-	expression tag
Val 13	-	expression tag
Asp 14	-	expression tag
Leu 15	-	expression tag
Gly 16	-	expression tag
Thr 17	-	expression tag
Glu 18	-	expression tag
Asn 19	-	expression tag
Leu 20	-	expression tag
Tyr 21	-	expression tag
Phe 22	-	expression tag
Gln 23	-	expression tag
Ser 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37327.1
Non-Polymers*	Number of molecules	5
	Total formula weight	596.7
All*	Total formula weight	37923.8

*Water molecules are not included.