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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6Y69

Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1a16S ribosomal RNApolymer1539498725.41GenBank (1108591457)Escherichia coli (strain K12)
2b30S ribosomal protein S2polymer21824253.91UniProt (P0A7V0)
Pfam (PF00318)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS2
3c30S ribosomal protein S3polymer20623078.81UniProt (P0A7V3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS3
4d30S ribosomal protein S4polymer20523383.01UniProt (P0A7V8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS4
5e30S ribosomal protein S5polymer15716532.11UniProt (P0A7W1)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS5
6f30S ribosomal protein S6polymer10011669.41UniProt (P02358)
Pfam (PF01250)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein bS6
7g30S ribosomal protein S7polymer15517506.21UniProt (P02359)
Pfam (PF00177)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS7
8h30S ribosomal protein S8polymer12914015.41UniProt (P0A7W7)
Pfam (PF00410)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS8
9i30S ribosomal protein S9polymer12714554.91UniProt (P0A7X3)
Pfam (PF00380)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS9
10j30S ribosomal protein S10polymer9811197.01UniProt (P0A7R5)
Pfam (PF00338)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS10
11k30S ribosomal protein S11polymer11612388.11UniProt (P0A7R9)
Pfam (PF00411)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS11
12l30S ribosomal protein S12polymer12313637.01UniProt (P0A7S3)
Pfam (PF00164)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS12
13m30S ribosomal protein S13polymer11412625.81UniProt (P0A7S9)
Pfam (PF00416)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS13
14n30S ribosomal protein S14polymer10111546.41UniProt (P0AG59)
Pfam (PF00253)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS14
15o30S ribosomal protein S15polymer8810159.61UniProt (P0ADZ4)
Pfam (PF00312)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS15
16p30S ribosomal protein S16polymer829207.61UniProt (P0A7T3)
Pfam (PF00886)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein bS16
17q30S ribosomal protein S17polymer809263.91UniProt (P0AG63)
Pfam (PF00366)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS17
18r30S ribosomal protein S18polymer657606.81UniProt (P0A7T7)
Pfam (PF01084)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein bS18
19s30S ribosomal protein S19polymer799057.61UniProt (P0A7U3)
Pfam (PF00203)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein uS19
20t30S ribosomal protein S20polymer859506.21UniProt (P0A7U7)
Pfam (PF01649)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein bS20
21u30S ribosomal protein S21polymer657763.11UniProt (P68679)
Pfam (PF01165)
In PDB		Escherichia coli (strain K12)Small ribosomal subunit protein bS21
22A23S ribosomal RNApolymer2903941305.31GenBank (939732440)Escherichia coli (strain K12)
23B5S ribosomal RNApolymer12038813.11GenBank (1373146531)Escherichia coli (strain K12)
24C50S ribosomal protein L2polymer27129663.21UniProt (P60422)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL2
25D50S ribosomal protein L3polymer20922277.51UniProt (P60438)
Pfam (PF00297)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL3
26E50S ribosomal protein L4polymer20122121.61UniProt (P60723)
Pfam (PF00573)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL4
27F50S ribosomal protein L5polymer17720073.21UniProt (P62399)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL5
28G50S ribosomal protein L6polymer17618801.61UniProt (P0AG55)
Pfam (PF00347)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL6
29H50S ribosomal protein L9polymer798258.31UniProt (P0A7R1)
Pfam (PF03948)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL9
30J50S ribosomal protein L13polymer14216050.61UniProt (P0AA10)
Pfam (PF00572)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL13
31K50S ribosomal protein L14polymer12213451.91UniProt (P0ADY3)
Pfam (PF00238)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL14
32L50S ribosomal protein L15polymer14314877.31UniProt (P02413)
Pfam (PF00828)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL15
33M50S ribosomal protein L16polymer13615312.31UniProt (P0ADY7)
Pfam (PF00252)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL16
34N50S ribosomal protein L17polymer12013721.91UniProt (P0AG44)
Pfam (PF01196)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL17
35O50S ribosomal protein L18polymer11612663.51UniProt (P0C018)
Pfam (PF00861)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL18
36P50S ribosomal protein L19polymer11413028.11UniProt (P0A7K6)
Pfam (PF01245)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL19
37Q50S ribosomal protein L20polymer11713396.81UniProt (P0A7L3)
Pfam (PF00453)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL20
38R50S ribosomal protein L21polymer10311586.41UniProt (P0AG48)
Pfam (PF00829)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL21
39S50S ribosomal protein L22polymer11012253.41UniProt (P61175)
Pfam (PF00237)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL22
40T50S ribosomal protein L23polymer9310546.51UniProt (P0ADZ0)
Pfam (PF00276)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL23
41U50S ribosomal protein L24polymer10211078.91UniProt (P60624)
Pfam (PF00467)
Pfam (PF17136)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL24
42V50S ribosomal protein L25polymer9410713.51UniProt (P68919)
Pfam (PF01386)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL25
43W50S ribosomal protein L27polymer758174.41UniProt (P0A7L8)
Pfam (PF01016)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL27
44X50S ribosomal protein L28polymer778896.41UniProt (P0A7M2)
Pfam (PF00830)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL28
45Y50S ribosomal protein L29polymer637286.51UniProt (P0A7M6)
Pfam (PF00831)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL29
46Z50S ribosomal protein L30polymer586423.61UniProt (P0AG51)
Pfam (PF00327)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein uL30
47050S ribosomal protein L32polymer566332.21UniProt (P0A7N4)
Pfam (PF01783)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL32
48150S ribosomal protein L33polymer505814.81UniProt (P0A7N9)
Pfam (PF00471)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL33
49250S ribosomal protein L34polymer465397.51UniProt (P0A7P5)
Pfam (PF00468)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL34
50350S ribosomal protein L35polymer647181.81UniProt (P0A7Q1)
Pfam (PF01632)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL35,Ribosomal protein A
51450S ribosomal protein L36polymer384377.41UniProt (P0A7Q6)
Pfam (PF00444)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL36-A,Ribosomal protein B
52650S ribosomal protein L31polymer667516.71UniProt (P0A7M9)
Pfam (PF01197)
In PDB		Escherichia coli (strain K12)Large ribosomal subunit protein bL31-A
53wE-site tRNApolymer7724771.81GenBank (1789840096)Escherichia coli (strain K12)
54xRibosome hibernation promoting factorpolymer9510768.21UniProt (P0AFX0)
Pfam (PF02482)
In PDB		Escherichia coli (strain K12)HPF,Hibernation factor HPF
55ATetracenomycin Xnon-polymer486.41Chemie (OCW)
56AMAGNESIUM IONnon-polymer24.32Chemie (MG)
Sequence modifications
n: 1 - 101 (UniProt: P0AG59)
PDBExternal DatabaseDetails
Ala 35-insertion
A: 1 - 2903 (GenBank: 939732440)
PDBExternal DatabaseDetails
C 747U 4191431conflict
G 1847A 4192531conflict
A 2069G 4192753conflict
B: 1 - 120 (GenBank: 1373146531)
PDBExternal DatabaseDetails
A 120U 4247873conflict
w: 1 - 76 (GenBank: 1789840096)
PDBExternal DatabaseDetails
U 29G 2435360conflict
A 41C 2435372conflict
x: 1 - 95 (UniProt: P0AFX0)
PDBExternal DatabaseDetails
Asp 57Asn 57conflict
Leu 61Ile 61conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains54
Total formula weight2140614.2
Non-Polymers*Number of molecules3
Total formula weight535.0
All*Total formula weight2141149.2
*Water molecules are not included.

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PDB entries from 2024-04-10

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