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6Y4O

Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Calmodulin-2polymer14916852.51UniProt (P0DP24)
Pfam (PF13499)
UniProt (by SIFTS) (P0DP23)
Homo sapiens (Human)
2B
(B)
Ryanodine receptor 2polymer303478.21UniProt (E9Q401)
UniProt (by SIFTS) (Q92736)
Mus musculus (Mouse)RyR2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,Type 2 ryanodine receptor
3C, D, E, F
(A)
CALCIUM IONnon-polymer40.14Chemie (CA)
4G, H
(A, B)
waterwater18.049Chemie (HOH)
Sequence modifications
B: 3614 - 3640 (UniProt: E9Q401)
PDBExternal DatabaseDetails
Ser 3611-expression tag
Asn 3612-expression tag
Ala 3613-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight20330.8
Non-Polymers*Number of molecules4
Total formula weight160.3
All*Total formula weight20491.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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