6Y4I
Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Thermolysin | polymer | 316 | 34360.3 | 1 | UniProt (P43133) | Geobacillus stearothermophilus | Neutral protease |
| 2 | B, C, D, E (E) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | F (E) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | G, H, I, J (E) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 5 | K (E) | N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine | non-polymer | 519.5 | 1 | Chemie (0PK) | |||
| 6 | L (E) | CESIUM ION | non-polymer | 132.9 | 1 | Chemie (CS) | |||
| 7 | M (E) | water | water | 18.0 | 362 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34360.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1190.7 | |
| All* | Total formula weight | 35551.0 |
