6Y1J

14-3-3 sigma in complex with IkappaBalpha pS63 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	14-3-3 protein sigma	polymer	253	28226.5	1	UniProt (P31947) Pfam (PF00244)	Homo sapiens (Human)	Epithelial cell marker protein 1,Stratifin
2	B (P)	NF-kappa-B inhibitor alpha	polymer	14	1676.7	1	UniProt (P25963)	Homo sapiens	I-kappa-B-alpha,IkappaBalpha,Major histocompatibility complex enhancer-binding protein MAD3
3	C, M (A)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	D (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	E (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6	F, G, H, I, J... (A)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
7	N, O (A, P)	water	water		18.0	334	Chemie (HOH)

Sequence modifications

A: 1 - 248 (UniProt: P31947)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

P: 57 - 69 (UniProt: P25963)

PDB	External Database	Details
Ace 56	-	acetylation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29903.2
Non-Polymers*	Number of molecules	11
	Total formula weight	784.6
All*	Total formula weight	30687.8

*Water molecules are not included.