6XZZ
Crystal structure of the BCL6 BTB domain in complex with the NCoR1 BBD2 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | B-cell lymphoma 6 protein | polymer | 126 | 14498.8 | 1 | UniProt (P41182) Pfam (PF00651) | Homo sapiens (Human) | BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51 |
| 2 | B (B) | Nuclear receptor corepressor 1 | polymer | 17 | 1865.1 | 1 | UniProt (O75376) | Homo sapiens | N-CoR1 |
| 3 | C, D, E, F, G... (A) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) | |||
| 4 | J, K (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | L (B) | trifluoroacetic acid | non-polymer | 114.0 | 1 | Chemie (TFA) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A: 6 - 129 (UniProt: P41182)
| PDB | External Database | Details |
|---|---|---|
| Gly 4 | - | expression tag |
| Pro 5 | - | expression tag |
| Gln 8 | Cys 8 | engineered mutation |
| Arg 67 | Cys 67 | engineered mutation |
| Asn 84 | Cys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 16363.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 345.9 | |
| All* | Total formula weight | 16709.7 |
