6XXT
The crystal structure of hCA II in complex with a 4-(4-aroylpiperazine-1-carbonyl)benzenesulfonamide derivative.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Carbonic anhydrase 2 | polymer | 262 | 29477.3 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | B (X) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (X) | 4-[4-(phenylcarbonyl)piperazin-1-yl]carbonylbenzenesulfonamide | non-polymer | 373.4 | 1 | Chemie (O42) | |||
| 4 | D (X) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (X) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
X: 1 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29477.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 530.9 | |
| All* | Total formula weight | 30008.2 |
