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6XXI

Crystal Structure of Human Deoxyhypusine Synthase in complex with NAD

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Deoxyhypusine synthasepolymer36941044.52UniProt (P49366)
Pfam (PF01916)
Homo sapiens (Human)DHS
2AA, C, CA, DA, E...
(B, A)
ACETATE IONnon-polymer59.014Chemie (ACT)
3BA, D, EA, FA, MA...
(B, A)
1,2-ETHANEDIOLnon-polymer62.118Chemie (EDO)
4G, HA
(A, B)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.42Chemie (NAD)
5H, I, IA, J
(A, B)
BETA-MERCAPTOETHANOLnon-polymer78.14Chemie (BME)
6X
(A)
FORMIC ACIDnon-polymer46.01Chemie (FMT)
7GA
(B)
(4R)-2-METHYLPENTANE-2,4-DIOLnon-polymer118.21Chemie (MRD)
8QA, RA
(A, B)
waterwater18.0356Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight82089.0
Non-Polymers*Number of molecules40
Total formula weight3747.4
All*Total formula weight85836.4
*Water molecules are not included.

248335

PDB entries from 2026-01-28

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