6XVO

Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Proto-oncogene tyrosine-protein kinase Src	polymer	79	8852.6	1	UniProt (P00523) Pfam (PF00018) In PDB	Gallus gallus (Chicken)	Proto-oncogene c-Src,pp60c-src,p60-Src
2	A	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
3	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
4		water	water		18.0	27	Chemie (HOH)

Sequence modifications

A: 82 - 141 (UniProt: P00523)

PDB	External Database	Details
Met 63	-	initiating methionine
Gly 64	-	expression tag
Ser 65	-	expression tag
Ser 66	-	expression tag
His 67	-	expression tag
His 68	-	expression tag
His 69	-	expression tag
His 70	-	expression tag
His 71	-	expression tag
His 72	-	expression tag
Ser 73	-	expression tag
Ser 74	-	expression tag
Gly 75	-	expression tag
Pro 76	-	expression tag
Gln 77	-	expression tag
Gln 78	-	expression tag
Gly 79	-	expression tag
Leu 80	-	expression tag
Arg 81	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	8852.6
Non-Polymers*	Number of molecules	3
	Total formula weight	362.4
All*	Total formula weight	9215.0

*Water molecules are not included.