6XVD
Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | Urokinase-type plasminogen activator | polymer | 253 | 28442.4 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (Human) | uPA |
| 2 | B (P) | upain-1-W3F | polymer | 12 | 1369.6 | 1 | synthetic construct | ||
| 3 | C, D (U, P) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
U: 16 - 250 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Cys 282 | engineered mutation |
| Gln 145 | Asn 305 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29812.0 | |
| All* | Total formula weight | 29812.0 |
