6XS9

Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Vacuolar protein sorting-associated protein 29	polymer	192	21636.9	1	UniProt (Q9UBQ0) Pfam (PF12850)	Homo sapiens (Human)	hVPS29,PEP11 homolog,Vesicle protein sorting 29
2	B (B)	Vacuolar protein sorting-associated protein 29	polymer	192	21652.9	1	UniProt (Q9UBQ0) Pfam (PF12850)	Homo sapiens (Human)	hVPS29,PEP11 homolog,Vesicle protein sorting 29
3	C, D, E, F (C, D, E, F)	48V-TYR-ILE-LYS-THR-PRO-LEU-GLY-THR-PHE-PRO-ASN-ARG-HIS-GLY	polymer	15	1764.0	4		synthetic construct
4	G, H (A)	MALONATE ION	non-polymer		102.0	2	Chemie (MLI)
5	I, J, K, M (A, B, F)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6	L (B)	1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE	non-polymer		264.3	1	Chemie (O4B)
7	N, O, P, Q, R (A, B, C, E, F)	water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 1 - 182 (UniProt: Q9UBQ0)

PDB	External Database	Details
Gly -9	-	expression tag
Ser -8	-	expression tag
Pro -7	-	expression tag
Glu -6	-	expression tag
Phe -5	-	expression tag
Gly -4	-	expression tag
Thr -3	-	expression tag
Arg -2	-	expression tag
Asp -1	-	expression tag
Arg 0	-	expression tag

B: 1 - 182 (UniProt: Q9UBQ0)

PDB	External Database	Details
Gly -9	-	expression tag
Ser -8	-	expression tag
Pro -7	-	expression tag
Glu -6	-	expression tag
Phe -5	-	expression tag
Gly -4	-	expression tag
Thr -3	-	expression tag
Arg -2	-	expression tag
Asp -1	-	expression tag
Arg 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	50345.9
Non-Polymers*	Number of molecules	7
	Total formula weight	836.8
All*	Total formula weight	51182.7

*Water molecules are not included.