6XR5

Crystal Structure of Diphosphomevalonate decarboxylase (MVD1) Cryptococcus neoformans var. grubii serotype A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Diphosphomevalonate decarboxylase	polymer	403	43908.7	8	UniProt (J9VRT5) Pfam (PF22700) Pfam (PF18376)	Cryptococcus neoformans var. grubii H99
2	I, J, L, M, O... (A, B, C, D, E...)	SULFATE ION	non-polymer		96.1	12	Chemie (SO4)
3	AA, K, N, R, T (H, A, B, D, E)	ADENINE	non-polymer		135.1	5	Chemie (ADE)
4	W, X (F, G)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	BA, CA, DA, EA, FA... (A, B, C, D, E...)	water	water		18.0	3549	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 395 (UniProt: J9VRT5)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	351269.8
Non-Polymers*	Number of molecules	19
	Total formula weight	1952.5
All*	Total formula weight	353222.3

*Water molecules are not included.