6XQI
Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein Vpr | polymer | 64 | 7623.7 | 4 | UniProt (P12520) | Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1) | R ORF protein,Viral protein R |
| 2 | E, F (F, G) | UV excision repair protein RAD23 homolog A | polymer | 40 | 4531.1 | 2 | UniProt (P54725) Pfam (PF00627) | Homo sapiens (Human) | hHR23A |
| 3 | G, H (H, I) | ASN-PRO-LEU-GLU-PHE-LEU | polymer | 6 | 731.8 | 2 | Homo sapiens (human) | ||
| 4 | I, J, K, L (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | M, N, O, P, Q... (A, B, C, D, F...) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 16 - 78 (UniProt: P12520)
| PDB | External Database | Details |
|---|---|---|
| Ala 15 | - | expression tag |
| Ser 77 | Arg 77 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 41020.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 41282.4 |
