6XPR

Human antibody D2 H1-1/H3-1 H3 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Hemagglutinin	polymer	291	32618.8	2	UniProt (R4L1D1) Pfam (PF00509)	Influenza A virus (A/Texas/50/2012(H3N2))
2	B, E (B, E)	antibody D2 H1-1/H3-1 H3 heavy chain	polymer	238	25692.9	2		Homo sapiens (Human)
3	C, F (C, F)	antibody D2 H1-1/H3-1 H3 light chain	polymer	214	23252.8	2		Homo sapiens (Human)
4	G, H (G, H)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
5	I (I)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	J, K, L (A, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, D: 37 - 319 (UniProt: R4L1D1)

PDB	External Database	Details
Gly 320	-	expression tag
Ala 321	-	expression tag
Leu 322	-	expression tag
Glu 323	-	expression tag
Val 324	-	expression tag
Leu 325	-	expression tag
Phe 326	-	expression tag
Gln 327	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	163128.9
Branched	Number of molecules	3
	Total formula weight	1597.5
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	165390.1

*Water molecules are not included.