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6XPF

Cryo-EM structure of human ZnT8 WT, in the absence of zinc, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Zinc transporter 8polymer32035088.12UniProt (Q8IWU4)
Pfam (PF01545)
Homo sapiens (Human)ZnT-8,Solute carrier family 30 member 8
2C, D, E, F
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight70176.3
Non-Polymers*Number of molecules4
Total formula weight261.6
All*Total formula weight70437.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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