6XPB
Structure of human GGT1 in complex with 2-amino-4-(((1-((carboxymethyl)amino)-1-oxobutan-2-yl)oxy)(phenoxy)phosphoryl)butanoic acid (ACPB) molecule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutathione hydrolase 1 heavy chain | polymer | 353 | 38533.7 | 1 | UniProt (P19440) Pfam (PF01019) | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 2 | B (B) | Glutathione hydrolase 1 light chain | polymer | 189 | 20014.4 | 1 | UniProt (P19440) Pfam (PF01019) | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 3 | C, D, E, F, G... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | H, K (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | I (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | L (B) | 2,2-diamino-4-[(S)-({(2S)-1-[(carboxymethyl)amino]-1-oxobutan-2-yl}oxy)(hydroxy)phosphanyl]butanoic acid | non-polymer | 401.4 | 1 | Chemie (V7D) | |||
| 7 | M, N (A, B) | water | water | 18.0 | 644 | Chemie (HOH) |
Sequence modifications
A: 28 - 380 (UniProt: P19440)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Val 272 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58548.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1822.5 | |
| All* | Total formula weight | 60370.6 |
