6XNP
Crystal Structure of Human STING CTD complex with SR-717
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of interferon protein | polymer | 189 | 21600.3 | 2 | UniProt (A0A2R3XZB7) Pfam (PF15009) UniProt (by SIFTS) (Q86WV6) | Homo sapiens (Human) | |
| 2 | C, E (A, B) | 4,5-difluoro-2-{[6-(1H-imidazol-1-yl)pyridazine-3-carbonyl]amino}benzoic acid | non-polymer | 345.3 | 2 | Chemie (V67) | |||
| 3 | D, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | F (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 353 | Chemie (HOH) |
Sequence modifications
A, B: 155 - 341 (UniProt: A0A2R3XZB7)
| PDB | External Database | Details |
|---|---|---|
| Gly 153 | - | expression tag |
| Ser 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43200.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 936.8 | |
| All* | Total formula weight | 44137.3 |
