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6XLW

Crystal structure of U2AF65 bound to AdML splice site sequence

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASplicing factor U2AF 65 kDa subunitpolymer20422237.31UniProt (P26368)
Pfam (PF00076)
In PDB
Homo sapiens (human)U2 auxiliary factor 65 kDa subunit,hU2AF65,U2 snRNP auxiliary factor large subunit
2BDNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3')polymer82449.31synthetic construct
3AGLYCEROLnon-polymer92.11Chemie (GOL)
4ADI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5ASODIUM IONnon-polymer23.04Chemie (NA)
6waterwater18.0259Chemie (HOH)
Sequence modifications
A: 141 - 341 (UniProt: P26368)
PDBExternal DatabaseDetails
Gly 138-expression tag
Pro 139-expression tag
Leu 140-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24686.6
Non-Polymers*Number of molecules6
Total formula weight290.2
All*Total formula weight24976.8
*Water molecules are not included.

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PDB entries from 2024-06-12

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