6XL1

crystal structure of cA4-activated Card1(D294N)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Card1	polymer	382	45012.1	2	UniProt (F2NWD3) Pfam (PF09002) In PDB	Treponema succinifaciens DSM 2489
2	C	cA4	polymer	4	1271.9	1		synthetic construct
3	A, B	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
4	B	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
5		water	water		18.0	552	Chemie (HOH)

Sequence modifications

A, B: 1 - 373 (UniProt: F2NWD3)

PDB	External Database	Details
Asn 294	Asp 294	engineered mutation
Gly 374	-	expression tag
Ser 375	-	expression tag
Gly 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	91296.0
Non-Polymers*	Number of molecules	5
	Total formula weight	458.1
All*	Total formula weight	91754.0

*Water molecules are not included.