6XKP

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-270

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Spike protein S1	polymer	231	26095.3	2	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
2	H, M	CV07-270 Heavy Chain	polymer	232	24817.8	2		Homo sapiens
3	L, N	CV07-270 Light Chain	polymer	216	22712.0	2		Homo sapiens
4	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	H, L, M, N	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)

Sequence modifications

A, B: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Ser 542	-	expression tag
Gly 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	147250.2
Non-Polymers*	Number of molecules	10
	Total formula weight	1210.9
All*	Total formula weight	148461.1

*Water molecules are not included.