6XJ8
KPC-2 N170A mutant bound to hydrolyzed imipenem at 2.05 A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbapenem-hydrolyzing beta-lactamase KPC | polymer | 293 | 31101.2 | 1 | UniProt (Q9F663) Pfam (PF00144) Pfam (PF13354) In PDB | Klebsiella pneumoniae | Carbapenem-hydrolyzing beta-lactamase KPC-1 |
| 2 | A | (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid | non-polymer | 317.4 | 1 | Chemie (8YF) | |||
| 3 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 1 - 295 (UniProt: Q9F663)
| PDB | External Database | Details |
|---|---|---|
| Ala 170 | Asn 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31101.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 317.4 | |
| All* | Total formula weight | 31418.6 |
