6XID

PCSK9(deltaCRD) in complex with cyclic peptide 51

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Proprotein convertase subtilisin/kexin type 9	polymer	122	13791.5	1	UniProt (Q8NBP7) Pfam (PF05922) In PDB	Homo sapiens (human)	Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9
2	B	Proprotein convertase subtilisin/kexin type 9	polymer	308	32836.9	1	UniProt (Q8NBP7) Pfam (PF00082) In PDB	Homo sapiens (human)	Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9
3	I	Peptide 51	polymer	11	1498.7	1		synthetic construct
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	329	Chemie (HOH)

Sequence modifications

B: 153 - 452 (UniProt: Q8NBP7)

PDB	External Database	Details
Asn 453	-	expression tag
Ser 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48127.1
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	48219.2

*Water molecules are not included.