6XES
Tubulin-RB3_SLD in complex with compound 40a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 438 | 48780.1 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (Pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta chain | polymer | 433 | 48648.7 | 2 | UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P02554) | Sus scrofa (Pig) | |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16851.1 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (Rat) | Stathmin-like protein B3,RB3 |
| 4 | F, K, M (A, C, D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 3 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | G, I, N (A, B, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | H (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 7 | J, O (B, D) | [6-(3-hydroxy-4-methylphenyl)pyrazin-2-yl](3,4,5-trimethoxyphenyl)methanone | non-polymer | 380.4 | 2 | Chemie (TU3) PubChem (156583241) | |||
| 8 | L (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 9 | P (D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) PubChem (679) | |||
| 10 | Q, R, S, T, U (A, B, C, D, E) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
E: 5 - 145 (UniProt: P63043)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Ala 4 | - | expression tag |
| Ala 14 | Cys 58 | engineered mutation |
| Trp 20 | Phe 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 211708.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3164.2 | |
| All* | Total formula weight | 214872.8 |
