6XER
Tubulin-RB3_SLD in complex with colchicine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Tubulin alpha-1B chain | polymer | 438 | 48780.1 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 2 | B, D | Tubulin beta chain | polymer | 433 | 48648.7 | 2 | UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P02554) In PDB | Sus scrofa (Pig) | |
| 3 | E | Stathmin-4 | polymer | 143 | 16851.1 | 1 | UniProt (P63043) Pfam (PF00836) In PDB | Rattus norvegicus (Rat) | Stathmin-like protein B3,RB3 |
| 4 | A, C, D | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 3 | Chemie (GTP) | |||
| 5 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | A, B, D | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 8 | B, D | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | non-polymer | 399.4 | 2 | Chemie (LOC) | |||
| 9 | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
E: 5 - 145 (UniProt: P63043)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Ala 4 | - | expression tag |
| Ala 14 | Cys 58 | engineered mutation |
| Trp 20 | Phe 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 211708.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3148.4 | |
| All* | Total formula weight | 214857.1 |
