6XCO

Immune receptor complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MHC class II HLA-DQ-alpha chain	polymer	193	21929.3	1	UniProt (Q30069)	Homo sapiens (Human)
2	B (B)	Hybrid Insulin Peptide, MHC class II HLA-DQ-beta-1 fusion	polymer	230	26071.0	1	UniProt (O19707)	Homo sapiens (Human)
3	C (D)	T-CELL-RECEPTOR, A1.9-alpha chain	polymer	205	22723.2	1		Homo sapiens (Human)
4	D (E)	T-CELL-RECEPTOR, A1.9-beta chain	polymer	240	27086.1	1		Homo sapiens (Human)
5	E, F, I (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	G, J, K, L, M... (A, B, D, E)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
7	H (A)	CACODYLATE ION	non-polymer		137.0	1	Chemie (CAC)
8	O, P, Q, R (A, B, D, E)	water	water		18.0	67	Chemie (HOH)

Sequence modifications

A: -1 - 181 (UniProt: Q30069)

PDB	External Database	Details
Cys 72	Ile 75	engineered mutation
Ser 182	-	expression tag
Thr 183	-	expression tag
Gly 184	-	expression tag
Gly 185	-	expression tag
Asp 186	-	expression tag
Asp 187	-	expression tag
Asp 188	-	expression tag
Asp 189	-	expression tag
Lys 190	-	expression tag

B: -2 - 12 (PDB: 6XCO)

PDB	External Database	Details
Gly 28	-	linker
Ser 29	-	linker
Gly 30	-	linker
Gly 31	-	linker
Ser 32	-	linker
Ile 33	-	linker
Glu 34	-	linker
Gly 35	-	linker
Arg 36	-	linker
Gly 37	-	linker
Gly 38	-	linker
Ser 39	-	linker
Gly 40	-	linker
Ala 41	-	linker
Ser 42	-	linker

B: 43 - 234 (UniProt: O19707)

PDB	External Database	Details
Thr 235	-	expression tag
Gly 236	-	expression tag
Gly 237	-	expression tag
Asp 238	-	expression tag
Asp 239	-	expression tag
Asp 240	-	expression tag
Asp 241	-	expression tag
Lys 242	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97809.4
Non-Polymers*	Number of molecules	10
	Total formula weight	1353.2
All*	Total formula weight	99162.6

*Water molecules are not included.