6XCG
Histone-lysine N-methyltransferase NSD2-PWWP1 with compound UNC6934
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone-lysine N-methyltransferase NSD2 | polymer | 141 | 16066.5 | 3 | UniProt (O96028) Pfam (PF00855) | Homo sapiens (Human) | Multiple myeloma SET domain-containing protein, MMSET, Nuclear SET domain-containing protein 2, Protein trithorax-5, Wolf-Hirschhorn syndrome candidate 1 protein |
| 2 | D, E, I (A, B, C) | N-cyclopropyl-3-oxo-N-({4-[(pyrimidin-4-yl)carbamoyl]phenyl}methyl)-3,4-dihydro-2H-1,4-benzoxazine-7-carboxamide | non-polymer | 443.5 | 3 | Chemie (V01) | |||
| 3 | F, G, H, J, K... (B, C) | UNKNOWN ATOM OR ION | non-polymer | 40.1 | 6 | Chemie (UNX) | |||
| 4 | M, N, O (A, B, C) | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence modifications
A, B, C: 211 - 350 (UniProt: O96028)
| PDB | External Database | Details |
|---|---|---|
| Gly 210 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48199.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1570.8 | |
| All* | Total formula weight | 49770.3 |
