6X8H
Caspase-8 in complex with AOMK inhibitor, Ac-DW3-KE, forms tetrahedral adduct
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-8 | polymer | 168 | 19148.7 | 1 | UniProt (Q14790) Pfam (PF00656) | Homo sapiens (Human) | CASP-8,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,ICE-like apoptotic protease 5,MORT1-associated ced-3 homolog,MACH |
| 2 | B (B) | Caspase-8 | polymer | 95 | 10901.4 | 1 | UniProt (Q14790) Pfam (PF00656) | Homo sapiens (Human) | CASP-8,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,ICE-like apoptotic protease 5,MORT1-associated ced-3 homolog,MACH |
| 3 | C (C) | Ac-DW3-KE | polymer | 6 | 837.0 | 1 | synthetic construct | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 30887.0 | |
| All* | Total formula weight | 30887.0 |
