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6X6A

Cryo-EM structure of NLRP1-DPP9 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, D)
Dipeptidyl peptidase 9polymer86398384.32UniProt (Q86TI2)
Pfam (PF19520)
Pfam (PF00930)
Pfam (PF00326)
Homo sapiens (Human)DP9,Dipeptidyl peptidase IV-related protein 2,DPRP-2,Dipeptidyl peptidase IX,DPP IX,Dipeptidyl peptidase-like protein 9,DPLP9
2B, F
(B, E)
NACHT, LRR and PYD domains-containing protein 1polymer1212136327.32UniProt (Q9C000)
Pfam (PF13516)
Pfam (PF13553)
Pfam (PF02758)
Pfam (PF05729)
Pfam (PF17779)
Pfam (PF17776)
Pfam (PF00560)
Homo sapiens (Human)Caspase recruitment domain-containing protein 7,Death effector filament-forming ced-4-like apoptosis protein,Nucleotide-binding domain and caspase recruitment domain
3C, D, G, H
(G, C, I, F)
NACHT, LRR and PYD domains-containing protein 1polymer26129760.74UniProt (Q9C000)
Pfam (PF00619)
Homo sapiens (Human)Caspase recruitment domain-containing protein 7,Death effector filament-forming ced-4-like apoptosis protein,Nucleotide-binding domain and caspase recruitment domain
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight588466.3
All*Total formula weight588466.3
*Water molecules are not included.

240971

PDB entries from 2025-08-27

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