6X5Q
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluA1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Calcium/calmodulin-dependent protein kinase type II subunit alpha | polymer | 268 | 30548.1 | 1 | UniProt (Q9UQM7) Pfam (PF00069) In PDB | Homo sapiens (Human) | CaMK-II subunit alpha |
2 | B | Glutamate receptor 1 | polymer | 20 | 2323.8 | 1 | UniProt (P42261) In PDB | Homo sapiens | GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GluA1 |
3 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 7 - 274 (UniProt: Q9UQM7)
PDB | External Database | Details |
---|---|---|
Asn 135 | Asp 135 | engineered mutation |
Lys 223 | Gln 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 32871.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 276.3 | |
All* | Total formula weight | 33148.1 |