6X2J
Structure of human TRPA1 in complex with agonist GNE551
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily A member 1 | polymer | 631 | 72622.1 | 4 | UniProt (O75762) Pfam (PF00023) Pfam (PF00520) | Homo sapiens (Human) | Ankyrin-like with transmembrane domains protein 1,Transformation-sensitive protein p120,Wasabi receptor |
| 2 | E, F, G, H (A, B, C, D) | 5-amino-1-[(4-bromo-2-fluorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-1H-1,2,3-triazole-4-carboxamide | non-polymer | 450.3 | 4 | Chemie (ULJ) |
Sequence modifications
A, B, C, D: 448 - 1078 (UniProt: O75762)
| PDB | External Database | Details |
|---|---|---|
| Asp 966 | Glu 966 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 290488.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1801.0 | |
| All* | Total formula weight | 292289.5 |
