6X1Z

Mre11 dimer in complex with small molecule modulator PFMJ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Nuclease SbcCD subunit D	polymer	336	38575.2	2	UniProt (Q9X1X0) Pfam (PF00149) Pfam (PF22155) In PDB	Thermotoga maritima
2	A, B	(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	non-polymer		281.4	2	Chemie (UL1)
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
5		water	water		18.0	343	Chemie (HOH)

Sequence modifications

A, B: 2 - 324 (UniProt: Q9X1X0)

PDB	External Database	Details
Met -11	-	initiating methionine
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Val 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77150.4
Non-Polymers*	Number of molecules	6
	Total formula weight	1001.8
All*	Total formula weight	78152.2

*Water molecules are not included.