6X1Y

Mre11 dimer in complex with small molecule modulator PFMI

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Nuclease SbcCD subunit D	polymer	336	38575.2	2	UniProt (Q9X1X0) Pfam (PF00149) Pfam (PF22155) In PDB	Thermotoga maritima
2	A, B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
3	A, B	(5Z)-5-[(3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	non-polymer		251.3	2	Chemie (UKV)
4		water	water		18.0	87	Chemie (HOH)

Sequence modifications

A, B: 2 - 324 (UniProt: Q9X1X0)

PDB	External Database	Details
Met -11	-	initiating methionine
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Val 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77150.4
Non-Polymers*	Number of molecules	4
	Total formula weight	893.1
All*	Total formula weight	78043.6

*Water molecules are not included.