6X1B
Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with the Product Nucleotide GpU.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Uridylate-specific endoribonuclease | polymer | 370 | 41657.2 | 2 | UniProt (P0DTD1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | pp1ab,ORF1ab polyprotein,NendoU,Non-structural protein 15,nsp15 |
2 | D, F | DNA (5'-R(*GP*U)-3') | polymer | 2 | 606.4 | 2 | synthetic construct | ||
3 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
4 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 347 (UniProt: P0DTD1)
PDB | External Database | Details |
---|---|---|
Met -22 | - | initiating methionine |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
Ser -15 | - | expression tag |
Ser -14 | - | expression tag |
Gly -13 | - | expression tag |
Val -12 | - | expression tag |
Asp -11 | - | expression tag |
Leu -10 | - | expression tag |
Gly -9 | - | expression tag |
Thr -8 | - | expression tag |
Glu -7 | - | expression tag |
Asn -6 | - | expression tag |
Leu -5 | - | expression tag |
Tyr -4 | - | expression tag |
Phe -3 | - | expression tag |
Gln -2 | - | expression tag |
Ser -1 | - | expression tag |
Asn 0 | - | expression tag |
Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 84527.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 376.1 | |
All* | Total formula weight | 84903.4 |