6WWK
KIF14[391-755] dimer two-heads-bound state - ADP-AlFx in complex with a microtubule
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, E) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (Pig) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
| 2 | B, E (B, I) | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 2 | UniProt (A0A287AGU7) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (A0A287AZ37) | Sus scrofa (Pig) | |
| 3 | C, F (K, N) | Kinesin-like protein KIF14 | polymer | 370 | 41196.4 | 2 | UniProt (L0N7N1) Pfam (PF00225) | Mus musculus (Mouse) | |
| 4 | G, M (A, E) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | H, N (A, E) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | I, O (B, I) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 7 | J, P (B, I) | TAXOL | non-polymer | 853.9 | 2 | Chemie (TA1) | |||
| 8 | K (K) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) | |||
| 9 | L, Q (K, N) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) |
Sequence modifications
K, N: 391 - 755 (UniProt: L0N7N1)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 282801.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 4627.6 | |
| All* | Total formula weight | 287429.1 |
