6WW1
Crystal structure of the LmFPPS mutant E97Y
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Farnesyl pyrophosphate synthase | polymer | 362 | 41051.3 | 2 | UniProt (Q4QBL1) Pfam (PF00348) | Leishmania major | |
| 2 | C, D, E, I, J... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 3 | F, L (A, B) | ISOPENTYL PYROPHOSPHATE | non-polymer | 248.1 | 2 | Chemie (IPR) | |||
| 4 | G, M (A, B) | 3-butyl-1-(2,2-diphosphonoethyl)pyridinium | non-polymer | 324.2 | 2 | Chemie (476) | |||
| 5 | H, N (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 6 | O, P (A, B) | water | water | 18.0 | 595 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 362 (UniProt: Q4QBL1)
| PDB | External Database | Details |
|---|---|---|
| Tyr 97 | Glu 97 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82102.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1503.2 | |
| All* | Total formula weight | 83605.7 |
