6WW1
Crystal structure of the LmFPPS mutant E97Y
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004161 | molecular_function | dimethylallyltranstransferase activity |
| A | 0004337 | molecular_function | geranyltranstransferase activity |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004161 | molecular_function | dimethylallyltranstransferase activity |
| B | 0004337 | molecular_function | geranyltranstransferase activity |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | ASP250 |
| A | 476405 |
| A | HOH521 |
| A | HOH529 |
| A | HOH542 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | HOH505 |
| A | HOH731 |
| A | ASP98 |
| A | ASP102 |
| A | CA403 |
| A | 476405 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASP98 |
| A | ASP102 |
| A | CA402 |
| A | 476405 |
| A | HOH565 |
| A | HOH579 |
| A | HOH648 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue IPR A 404 |
| Chain | Residue |
| A | GLY47 |
| A | LYS48 |
| A | ARG51 |
| A | GLN91 |
| A | ARG108 |
| A | THR208 |
| A | TYR211 |
| A | PHE246 |
| A | GLN247 |
| A | ASP250 |
| A | 476405 |
| A | HOH523 |
| A | HOH555 |
| A | HOH597 |
| A | HOH610 |
| A | HOH636 |
| A | HOH642 |
| A | HOH688 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue 476 A 405 |
| Chain | Residue |
| A | PHE94 |
| A | ASP98 |
| A | ASP102 |
| A | ARG107 |
| A | GLN167 |
| A | LYS207 |
| A | THR208 |
| A | ASP250 |
| A | LYS264 |
| A | CA401 |
| A | CA402 |
| A | CA403 |
| A | IPR404 |
| A | HOH578 |
| A | HOH648 |
| A | HOH678 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue ACT A 406 |
| Chain | Residue |
| A | ASP254 |
| A | GLY266 |
| A | THR267 |
| A | ASP268 |
| A | ILE269 |
| A | GLU270 |
| A | VAL305 |
| A | LYS309 |
| A | HOH672 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 401 |
| Chain | Residue |
| B | ASP250 |
| B | 476405 |
| B | HOH501 |
| B | HOH590 |
| B | HOH683 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 402 |
| Chain | Residue |
| B | ASP98 |
| B | ASP102 |
| B | CA403 |
| B | 476405 |
| B | HOH516 |
| B | HOH703 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 403 |
| Chain | Residue |
| B | ASP98 |
| B | ASP102 |
| B | CA402 |
| B | 476405 |
| B | HOH556 |
| B | HOH562 |
| B | HOH577 |
| site_id | AD1 |
| Number of Residues | 16 |
| Details | binding site for residue IPR B 404 |
| Chain | Residue |
| B | GLY47 |
| B | LYS48 |
| B | ARG51 |
| B | GLN91 |
| B | ARG108 |
| B | TYR211 |
| B | GLN247 |
| B | ASP250 |
| B | 476405 |
| B | HOH523 |
| B | HOH527 |
| B | HOH547 |
| B | HOH573 |
| B | HOH609 |
| B | HOH627 |
| B | HOH647 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residue 476 B 405 |
| Chain | Residue |
| B | LYS207 |
| B | THR208 |
| B | ASP250 |
| B | LYS264 |
| B | CA401 |
| B | CA402 |
| B | CA403 |
| B | IPR404 |
| B | HOH501 |
| B | HOH556 |
| B | HOH592 |
| B | HOH604 |
| B | ASP98 |
| B | ASP102 |
| B | ARG107 |
| B | GLN167 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue ACT B 406 |
| Chain | Residue |
| B | ASP254 |
| B | GLY266 |
| B | THR267 |
| B | ASP268 |
| B | ILE269 |
| B | GLU270 |
| B | VAL305 |
| B | LYS309 |
Functional Information from PROSITE/UniProt
