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6WTH

Full-length human ENaC ECD

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Amiloride-sensitive sodium channel subunit alphapolymer66975780.51UniProt (P37088)
Pfam (PF00858)
Homo sapiens (Human)Alpha-NaCH,Epithelial Na(+) channel subunit alpha,ENaCA,Nonvoltage-gated sodium channel 1 subunit alpha,SCNEA
2B
(B)
Amiloride-sensitive sodium channel subunit betapolymer64072728.91UniProt (P51168)
Pfam (PF00858)
Homo sapiens (Human)Beta-NaCH,Epithelial Na(+) channel subunit beta,ENaCB,Nonvoltage-gated sodium channel 1 subunit beta,SCNEB
3C
(C)
Amiloride-sensitive sodium channel subunit gammapolymer64974353.01UniProt (P51170)
Pfam (PF00858)
Homo sapiens (Human)Epithelial Na(+) channel subunit gamma,Gamma-ENaC,Gamma-NaCH,Nonvoltage-gated sodium channel 1 subunit gamma,SCNEG
4D, E
(D, E)
7B1 Fabpolymer11810060.42Mus musculus (mouse)
5F, G
(F, G)
10D4 Fabpolymer1159805.12Mus musculus (mouse)
6H, I, J
(H, I, J)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.43In PDB
GlyTouCan (G42666HT)
7K
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
8L, M, N, O
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight262593.3
BranchedNumber of molecules3
Total formula weight1273.2
Non-Polymers*Number of molecules5
Total formula weight907.8
All*Total formula weight264774.4
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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