6WMZ
Crystal structure of human SFPQ/NONO complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Splicing factor, proline- and glutamine-rich | polymer | 388 | 44759.4 | 2 | UniProt (P23246) Pfam (PF00076) Pfam (PF08075) | Homo sapiens (Human) | 100 kDa DNA-pairing protein,hPOMp100,DNA-binding p52/p100 complex,100 kDa subunit,Polypyrimidine tract-binding protein-associated-splicing factor,PTB-associated-splicing factor |
| 2 | B, D (B, D) | Non-POU domain-containing octamer-binding protein | polymer | 261 | 30278.7 | 2 | UniProt (Q15233) Pfam (PF00076) Pfam (PF08075) | Homo sapiens (Human) | NonO protein,54 kDa nuclear RNA- and DNA-binding protein,55 kDa nuclear protein,DNA-binding p52/p100 complex,52 kDa subunit,NMT55,p54(nrb),p54nrb |
| 3 | E (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, C: 214 - 598 (UniProt: P23246)
B, D: 53 - 312 (UniProt: Q15233)
| PDB | External Database | Details |
|---|---|---|
| Gly 211 | - | expression tag |
| Ala 212 | - | expression tag |
| Met 213 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 52 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 150076.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 150172.3 |
