6WMV
Structure of a phosphatidylinositol-phosphate synthase (PIPS) from Mycobacterium kansasii with evidence of substrate binding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | AfCTD-Phosphatidylinositol-phosphate synthase (PIPS) fusion | polymer | 370 | 40388.8 | 2 | UniProt (A0A101DFK9) UniProt (U5WZP7) Pfam (PF21682) UniProt (by SIFTS) (O27985) | Archaeoglobus fulgidus | |
| 2 | C (A) | L-MYO-INOSITOL-1-PHOSPHATE | non-polymer | 258.1 | 1 | Chemie (LIP) | |||
| 3 | D, E, F, S (A, C) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | G (A) | 3,3',3''-phosphanetriyltripropanoic acid | non-polymer | 250.2 | 1 | Chemie (TCE) | |||
| 5 | H, T (A, C) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 6 | I, J, K, U, V... (A, C) | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 7 | Chemie (OLC) | |||
| 7 | L, M, N, O, Y... (A, C) | Octadecane | non-polymer | 254.5 | 6 | Chemie (8K6) | |||
| 8 | AA, BA, P (C, A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 9 | Q (C) | CYTIDINE-5'-MONOPHOSPHATE | non-polymer | 323.2 | 1 | Chemie (C5P) | |||
| 10 | R (C) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 11 | CA, DA (A, C) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A, C: -139 - -5 (UniProt: A0A101DFK9)
A, C: 2 - 232 (UniProt: U5WZP7)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | linker |
| Ser -1 | - | linker |
| Gly 0 | - | linker |
| Ser 1 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 17 | Asp 17 | engineered mutation |
| Leu 77 | Gln 77 | engineered mutation |
| Ser 79 | Gly 79 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80777.6 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 5888.1 | |
| All* | Total formula weight | 86665.7 |
